DKK3 抗体 (N-Term)
Quick Overview for DKK3 抗体 (N-Term) (ABIN2798864)
抗原
See all DKK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 15-45, N-Term
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原理
- Rabbit Anti-Human DKK3 (N-term) Antibody
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免疫原
- This DKK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-45 amino acids from the N-terminal region of human DKK3.
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亚型
- Ig Fraction
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anti-DKK3 (AA 23-349) antibody
适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-DKK3 (AA 91-350) antibody适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 8A5C6 unconjugated
anti-DKK3 (AA 91-350) antibody适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal unconjugated
anti-DKK3 (AA 31-130) antibody适用: 小鼠, 兔 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-DKK3 (AA 22-350) antibody适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-DKK3 (AA 22-350) antibody适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-DKK3 antibody适用: 人, 猴 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 4G7 unconjugated
anti-DKK3 (AA 41-348) antibody适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-DKK3 (C-Term) antibodyVerified 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-DKK3 antibody适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
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应用备注
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100Western blot analysis of lysates from 293, 293T, A549, HL-60, MCF-7 cell line and mouse brain tissue lysate (from left to right), using DKK3 Antibody (A30), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.500 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- DKK3
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背景
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Target Description: DKK3, like DKK1, DKK2, and DKK4, possesses an N-terminal signal peptide and 2 conserved cysteine-rich domains, which are separated by a linker region and contain 10 cysteine residues each. The second cysteine region has a putative lipid-binding function that may facilitate WNT/DKK interactions at the plasma membrane. The linker region contains 50 to 55 amino acids in DKK1, DKK2, and DKK4, whereas in DKK3 it contains only 12 amino acids. All DKKs have several potential sites for cleavage by furin-type proteases. Northern blot analysis revealed wide expression of the DKK3 transcript, with highest expression in heart, brain, and spinal cord. In situ hybridization reveals highest expression in mouse brain, eye, and heart.
Gene Symbol: DKK3
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分子量
- 38390 Da
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基因ID
- 27122
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UniProt
- Q9UBP4
抗原
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