MXI1 抗体 (Center)
Quick Overview for MXI1 抗体 (Center) (ABIN2798843)
抗原
See all MXI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 53-82, Center
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原理
- Rabbit Anti-Mouse MXI1 (Center) Antibody
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免疫原
- This MXI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-82 amino acids from the Central region of human MXI1.
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亚型
- Ig Fraction
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应用备注
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Western Blot
Recommended Dilutions
WB: 1:1000MXI1 Antibody (Center) . -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- MXI1 (MAX Interactor 1 (MXI1))
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别名
- MXI1
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背景
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Target Description: Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.
Gene Symbol: MXI1
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分子量
- 26062 Da
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基因ID
- 4601
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UniProt
- P50539
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途径
- Maintenance of Protein Location
抗原
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