S100B 抗体 (Center)
Quick Overview for S100B 抗体 (Center) (ABIN2798824)
抗原
See all S100B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 28-56, Center
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原理
- Rabbit Anti-Human S100B/S-100 (Center) Antibody
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免疫原
- This S100B/S-100 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the Central region of human S100B/S-100.
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亚型
- Ig Fraction
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应用备注
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Western Blot
Recommended Dilutions
WB: 1:1000S100B/S-100 Antibody (Center) . -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.500 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- S100B (S100 Calcium Binding Protein B (S100B))
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别名
- S100B/S-100
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背景
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Target Description: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21, however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
Gene Symbol: S100B
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分子量
- 10713 Da
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基因ID
- 6285
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UniProt
- P04271
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途径
- Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
抗原
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