PCGF2 抗体 (Center)
Quick Overview for PCGF2 抗体 (Center) (ABIN2798813)
抗原
See all PCGF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 121-150, Center
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原理
- Rabbit Anti-Human PCGF2 (Center) Antibody
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免疫原
- This PCGF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-150 amino acids from the Central region of human PCGF2.
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亚型
- Ig Fraction
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应用备注
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Western Blot
Recommended Dilutions
WB: 1:1000PCGF2 Antibody (Center) . -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.450 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))
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别名
- PCGF2
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背景
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Target Description: The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.
Gene Symbol: PCGF2
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分子量
- 37788 Da
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基因ID
- 7703
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UniProt
- P35227
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途径
- Chromatin Binding
抗原
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