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PDZK1 抗体 (Center)

The 兔 多克隆 anti-PDZK1 antibody is suitable to detect PDZK1 in samples from 人. It has been validated for WB 和 IHC.
产品编号 ABIN2798783
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PDZK1 抗体 (Center) (ABIN2798783)

抗原

See all PDZK1 抗体
PDZK1 (PDZ Domain Containing 1 (PDZK1))

适用

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宿主

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克隆类型

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多克隆

标记

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This PDZK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 196-224, Center

    原理

    Rabbit Anti-Human PDZK1 (Center) Antibody

    免疫原

    This PDZK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-224 amino acids from the Central region of human PDZK1.

    亚型

    Ig Fraction
  • 应用备注

    Western Blot, Immunohistochemistry
    Recommended Dilutions
    WB: 1:1000, IHC: 1:10-50PDZK1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.350 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    PDZK1 (PDZ Domain Containing 1 (PDZK1))

    别名

    PDZK1

    背景

    Target Description: A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. May function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function (By similarity).

    Gene Symbol: PDZK1

    分子量

    57129 Da

    基因ID

    5174

    UniProt

    Q5T2W1
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