TADA3L 抗体 (C-Term)
Quick Overview for TADA3L 抗体 (C-Term) (ABIN2798740)
抗原
See all TADA3L (TADA3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 386-414, C-Term
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原理
- Rabbit Anti-Human TADA3L (C-term) Antibody
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免疫原
- This TADA3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-414 amino acids from the C-terminal region of human TADA3L.
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亚型
- Ig Fraction
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应用备注
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Western Blot, Immunofluorescence
Recommended Dilutions
WB: 1:1000, IF: 1:10-50TADA3L Antibody (C-term) . TADA3L immunoreactivity is localized to Nucleus significantly. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))
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别名
- TADA3L
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背景
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Target Description: Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq].
Gene Symbol: TADA3
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分子量
- 48902 Da
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基因ID
- 10474
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UniProt
- O75528
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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