RUNX3 抗体 (Center)
Quick Overview for RUNX3 抗体 (Center) (ABIN2798697)
抗原
See all RUNX3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 168-197, Center
-
原理
- Rabbit Anti-Human RUNX3 (Center) Antibody
-
免疫原
- This RUNX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-197 amino acids from the Central region of human RUNX3.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
-
Western Blot, Immunohistochemistry, Immunofluorescence
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, IF: 1:10-50Western blot analysis of lysates from HL-60, Jurkat cell line (from left to right), using RUNX3 Antibody (Center) . RUNX3 immunoreactivity is localized to Nucleus and Cytoplasm significantly. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
储存条件
- 4 °C,-20 °C
-
储存方法
- 2-8°C (short-term), -20°C (long-term)
-
-
- RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
-
别名
- RUNX3
-
背景
-
Target Description: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Symbol: RUNX3
-
分子量
- 44356 Da
-
基因ID
- 864
-
UniProt
- Q13761
抗原
-