SNX6 抗体 (N-Term)
-
- 抗原 See all SNX6 抗体
- SNX6 (Sorting Nexin 6 (SNX6))
-
抗原表位
- AA 81-110, N-Term
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This SNX6 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 原理
- Rabbit Anti-Human SNX6 (N-term) Antibody
- 免疫原
- This SNX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-110 amino acids from the N-terminal region of human SNX6.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product SNX6 Primary Antibody
-
-
- 应用备注
-
Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of SNX6 Antibody (N-term) was detected using the purified Pab. - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 2.0 mg/mL
- 储存条件
- 4 °C,-20 °C
- 储存方法
- 2-8°C (short-term), -20°C (long-term)
-
- 抗原
- SNX6 (Sorting Nexin 6 (SNX6))
- 别名
- SNX6 (SNX6 产品)
- 别名
- MGC75952 antibody, MGC80251 antibody, im:7146294 antibody, wu:fa55b10 antibody, zgc:110798 antibody, MSTP010 antibody, TFAF2 antibody, 2010006G21Rik antibody, 2610032J07Rik antibody, 2810425K19Rik antibody, AU018928 antibody, C85963 antibody, sorting nexin 6 antibody, sorting nexin 6 L homeolog antibody, snx6 antibody, snx6.L antibody, SNX6 antibody, Snx6 antibody
- 背景
-
Target Description: SNX6 interacts with members of the transforming growth factor-beta family of receptor serine-threonine kinases. These receptors belong to two classes: type II receptors that bind ligand, and type I receptors that are subsequently recruited to transduce the signal. Of the type II receptors, SNX6 was found to interact strongly with ActRIIB and more moderately with wild type and kinase-defective mutants of TbetaRII. Of the type I receptors, SNX6 was found to interact only with inactivated TbetaRI. SNXs 1-4 also interacted with the transforming growth factor-beta receptor family, showing different receptor preferences. Conversely, SNX6 behaved similarly to the other SNX proteins in its interactions with receptor tyrosine kinases. Strong heteromeric interactions were also seen among SNX1, -2, -4, and -6, suggesting the formation in vivo of oligomeric complexes. These findings are the first evidence for the association of the SNX family of molecules with receptor serine-threonine kinases.
Gene Symbol: SNX6
- 分子量
- 46649 Da
- 基因ID
- 58533
- UniProt
- Q9UNH7
- 途径
- EGFR Signaling Pathway
-