E2F3 抗体 (Center)
Quick Overview for E2F3 抗体 (Center) (ABIN2798668)
抗原
See all E2F3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 151-180, Center
-
原理
- Rabbit Anti-Human E2F3 (Center) Antibody
-
免疫原
- This E2F3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the Central region of human E2F3.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
-
Western Blot
Recommended Dilutions
WB: 1:1000E2F3 Antibody (Center) . -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.350 mg/mL
-
储存条件
- 4 °C,-20 °C
-
储存方法
- 2-8°C (short-term), -20°C (long-term)
-
-
- E2F3
-
背景
-
Target Description: The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner.
Gene Symbol: E2F3
-
分子量
- 49162 Da
-
基因ID
- 1871
-
UniProt
- O00716
抗原
-