HNMT 抗体 (N-Term)
Quick Overview for HNMT 抗体 (N-Term) (ABIN2798592)
抗原
See all HNMT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 29-58, N-Term
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原理
- Rabbit Anti-Human HNMT (N-term) Antibody
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免疫原
- This HNMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human HNMT.
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亚型
- Ig Fraction
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应用备注
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Immunofluorescence, Western Blot, Immunohistochemistry
Recommended Dilutions
IF: 1:10-50, WB: 1:1000, IHC: 1:10-50Confocal immunofluorescent analysis of HNMT Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 2.0 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- HNMT (Histamine N-Methyltransferase (HNMT))
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别名
- HNMT
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背景
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Target Description: In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. HNMT is the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells.
Gene Symbol: HNMT
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分子量
- 33295 Da
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基因ID
- 3176
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UniProt
- P50135
抗原
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