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PRDM6 抗体 (N-Term)

This anti-PRDM6 antibody is a 兔 多克隆 antibody detecting PRDM6 in WB. Suitable for 人.
产品编号 ABIN2798584
发货至: 中国

Quick Overview for PRDM6 抗体 (N-Term) (ABIN2798584)

抗原

See all PRDM6 抗体
PRDM6 (PR Domain Containing 6 (PRDM6))

适用

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宿主

  • 17

克隆类型

  • 17
多克隆

标记

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This PRDM6 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 8
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    AA 44-72, N-Term

    原理

    Rabbit Anti-Human PRDM6 (N-term) Antibody

    免疫原

    This PRDM6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-72 amino acids from the N-terminal region of human PRDM6.

    亚型

    Ig Fraction
  • 应用备注

    Western Blot
    Recommended Dilutions
    WB: 1:1000PRDM6 Antibody (N-term) .

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.350 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    PRDM6 (PR Domain Containing 6 (PRDM6))

    别名

    PRDM6

    背景

    Target Description: Putative histone methyltransferase that acts as a transcriptional repressor of smooth muscle gene expression. Promotes the transition from differentiated to proliferative smooth muscle by suppressing differentiation and maintaining the proliferative potential of vascular smooth muscle cells. Also plays a role in endothelial cells by inhibiting endothelial cell proliferation, survival and differentiation. It is unclear whether it has histone methyltransferase activity in vivo. According to some authors, it does not act as a histone methyltransferase by itself and represses transcription by recruiting EHMT2/G9a. According to others, it possesses histone methyltransferase activity when associated with other proteins and specifically methylates 'Lys-20' of histone H4 in vitro. 'Lys-20' methylation represents a specific tag for epigenetic transcriptional repression (By similarity).

    Gene Symbol: PRDM6

    分子量

    64452 Da

    基因ID

    93166

    UniProt

    Q9NQX0

    途径

    Regulation of Muscle Cell Differentiation
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