LIM Domain Binding 2 Protein 抗体 (C-Term)
Quick Overview for LIM Domain Binding 2 Protein 抗体 (C-Term) (ABIN2798567)
抗原
See all LIM Domain Binding 2 Protein (LDB2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 314-342, C-Term
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原理
- Rabbit Anti-Human LDB2 (C-term) Antibody
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免疫原
- This LDB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-342 amino acids from the C-terminal region of human LDB2.
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亚型
- Ig Fraction
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应用备注
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50LDB2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.400 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- LIM Domain Binding 2 Protein (LDB2) (LIM Domain Binding 2 (LDB2))
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别名
- LDB2
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背景
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Target Description: Genes encoding LIM domain-binding factors were initially isolated in a screen for proteins that physically interact with the LIM domains of nuclear proteins (summarized by Semina et al., 1998 [PubMed 9799849]). These proteins, such as the one encoded by the LDB2 gene, are capable of binding to a variety of transcription factors and are likely to function at enhancers to bring together diverse transcription factors and form higher order activation complexes or to block formation of such complexes (Jurata and Gill, 1997 [PubMed 9315627]). The family of genes encoding LIM domain-binding factors includes 2 members isolated from the mouse, Clim1 (Bach et al., 1997 [PubMed 9192866]) and Clim2/Lbd1/Nli (Agulnick et al., 1996 [PubMed 8918878], Jurata et al., 1996 [PubMed 8876198], Bach et al., 1997 [PubMed 9192866]) and their homologs cloned from the frog, chicken, and fly. The fact that LIM domain-binding factors are likely to be involved in the coordination of the transcriptional activity of many diverse factors might implicate them in human phenotypes characterized by multiple affected sites.
Gene Symbol: LDB2
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分子量
- 42793 Da
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基因ID
- 9079
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UniProt
- O43679
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途径
- Stem Cell Maintenance
抗原
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