CSTB 抗体 (Center)
Quick Overview for CSTB 抗体 (Center) (ABIN2798556)
抗原
See all CSTB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 10-39, Center
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原理
 - Rabbit Anti-Human CSTB (Center) Antibody
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免疫原
 - This CSTB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from the Central region of human CSTB.
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亚型
 - Ig Fraction
 
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应用备注
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                        Western Blot
Recommended Dilutions
WB: 1:1000CSTB Antibody (Center) . - 
                                            
限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 0.5 mg/mL
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储存条件
 - 4 °C,-20 °C
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储存方法
 - 2-8°C (short-term), -20°C (long-term)
 
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- CSTB (Cystatin B (Stefin B) (CSTB))
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别名
 - CSTB
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背景
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Target Description: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).
Gene Symbol: CSTB
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分子量
 - 11140 Da
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基因ID
 - 1476
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UniProt
 - P04080
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途径
 - Response to Water Deprivation
 
抗原
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