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CRTC2 抗体 (N-Term)

This anti-CRTC2 antibody is a 兔 多克隆 antibody detecting CRTC2 in WB 和 IHC. Suitable for 人.
产品编号 ABIN2798540
发货至: 中国

Quick Overview for CRTC2 抗体 (N-Term) (ABIN2798540)

抗原

See all CRTC2 抗体
CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

适用

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宿主

  • 74
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克隆类型

  • 58
  • 27
多克隆

标记

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This CRTC2 antibody is un-conjugated

应用范围

  • 71
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 94-123, N-Term

    原理

    Rabbit Anti-Human CRTC2 (N-term) Antibody

    免疫原

    This CRTC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-123 amino acids from the N-terminal region of human CRTC2.

    亚型

    Ig Fraction
  • 应用备注

    Western Blot, Immunohistochemistry
    Recommended Dilutions
    WB: 1:1000, IHC: 1:10-50CRTC2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.420 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

    别名

    CRTC2

    背景

    Target Description: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).

    Gene Symbol: CRTC2

    分子量

    73302 Da

    基因ID

    200186

    UniProt

    Q53ET0

    途径

    AMPK Signaling, Carbohydrate Homeostasis
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