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Stanniocalcin 2 抗体 (C-Term)

This anti-Stanniocalcin 2 antibody is a 兔 多克隆 antibody detecting Stanniocalcin 2 in WB 和 IHC. Suitable for 小鼠.
产品编号 ABIN2798536
发货至: 中国

Quick Overview for Stanniocalcin 2 抗体 (C-Term) (ABIN2798536)

抗原

See all Stanniocalcin 2 (STC2) 抗体
Stanniocalcin 2 (STC2)

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This Stanniocalcin 2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 273-302, C-Term

    原理

    Rabbit Anti-Mouse STC2 (C-term) Antibody

    免疫原

    This STC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-302 amino acids from the C-terminal region of human STC2.

    亚型

    Ig Fraction
  • 应用备注

    Western Blot, Immunohistochemistry
    Recommended Dilutions
    WB: 1:1000, IHC: 1:10-50STC2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    Stanniocalcin 2 (STC2)

    别名

    STC2

    背景

    Target Description: This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.

    Gene Symbol: STC2

    分子量

    33249 Da

    基因ID

    8614

    UniProt

    O76061

    途径

    Hormone Activity, ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome
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