Stanniocalcin 2 抗体 (C-Term)
Quick Overview for Stanniocalcin 2 抗体 (C-Term) (ABIN2798536)
抗原
See all Stanniocalcin 2 (STC2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 273-302, C-Term
-
原理
- Rabbit Anti-Mouse STC2 (C-term) Antibody
-
免疫原
- This STC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-302 amino acids from the C-terminal region of human STC2.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
-
Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50STC2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
储存条件
- 4 °C,-20 °C
-
储存方法
- 2-8°C (short-term), -20°C (long-term)
-
-
- Stanniocalcin 2 (STC2)
-
别名
- STC2
-
背景
-
Target Description: This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.
Gene Symbol: STC2
-
分子量
- 33249 Da
-
基因ID
- 8614
-
UniProt
- O76061
-
途径
- Hormone Activity, ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome
抗原
-