RNF19A 抗体 (Center)
Quick Overview for RNF19A 抗体 (Center) (ABIN2798497)
抗原
See all RNF19A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 384-413, Center
-
原理
- Rabbit Anti-Human RNF19A (Center) Antibody
-
免疫原
- This RNF19A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 384-413 amino acids from the Central region of human RNF19A.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
-
Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50RNF19A Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
储存条件
- 4 °C,-20 °C
-
储存方法
- 2-8°C (short-term), -20°C (long-term)
-
-
- RNF19A (Ring Finger Protein 19A (RNF19A))
-
别名
- RNF19A
-
背景
-
Target Description: The protein encoded this gene contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB. Alternatively spliced transcript variants encoding the same protein have been reported.
Gene Symbol: RNF19A
-
分子量
- 90696 Da
-
基因ID
- 25897
-
UniProt
- Q9NV58
抗原
-