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Deoxyuridine Triphosphatase (DUT) (AA 170-198), (C-Term) 抗体

This anti- antibody is a 兔多克隆 antibody detecting in WB 和 IHC. Suitable for 人.

产品编号 ABIN2798480

发货至: 中国

Quick Overview for Deoxyuridine Triphosphatase (DUT) (AA 170-198), (C-Term) 抗体 (ABIN2798480)

抗原

See all Deoxyuridine Triphosphatase (DUT) 抗体

Deoxyuridine Triphosphatase (DUT)

适用

80
33
18
3
2
1
1
1
1
1
1

人

宿主

兔

克隆类型

多克隆

标记

30
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1

非结合性

应用范围

63
26
26
22
18
15
8
6
4
1
1

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product DUT Primary Antibody

抗原表位
15

15

8

7

3

3

2

2

1

1

1

1

1

1

1

1
AA 170-198, C-Term

原理

Rabbit Anti-Human DUT (C-term) Antibody

免疫原

This DUT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-198 amino acids from the C-terminal region of human DUT.

亚型

Ig Fraction
anti-Deoxyuridine Triphosphatase (DUT) (AA 68-164) antibody
DUT 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 1C9 unconjugated

anti-Deoxyuridine Triphosphatase (DUT) antibody
DUT 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Deoxyuridine Triphosphatase (DUT) (AA 89-252) antibody
DUT 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Deoxyuridine Triphosphatase (DUT) (Internal Region) antibody
Verified DUT 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Deoxyuridine Triphosphatase (DUT) (C-Term) antibody
DUT 适用: 人, 大鼠, 小鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Deoxyuridine Triphosphatase (DUT) (AA 151-252) antibody
DUT 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Deoxyuridine Triphosphatase (DUT) antibody
DUT 适用: 人, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Deoxyuridine Triphosphatase (DUT) (AA 1-252) antibody
DUT 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Deoxyuridine Triphosphatase (DUT) (C-Term) antibody
DUT 适用: 人, 大鼠, 小鼠, 犬, Bat, 豚鼠, 马, Saccharomyces cerevisiae, 斑马鱼 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Deoxyuridine Triphosphatase (DUT) (N-Term) antibody
DUT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50Western blot analysis of lysate from A431 cell line, using DUT Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

限制

仅限研究用
状态

Liquid

浓度

0.5 mg/mL

储存条件

4 °C,-20 °C

储存方法

2-8°C (short-term), -20°C (long-term)
抗原

Deoxyuridine Triphosphatase (DUT)

别名

DUT

背景

Target Description: This gene encodes an essential enzyme of nucleotide metabolism. The encoded protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. Alternative splicing of this gene leads to different isoforms that localize to either the mitochondrion or nucleus. A related pseudogene is located on chromosome 19.
Gene Symbol: DUT

分子量

26563 Da

基因ID

1854

UniProt

P33316

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