CDH6 抗体 (C-Term)
Quick Overview for CDH6 抗体 (C-Term) (ABIN2798460)
抗原
See all CDH6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 665-695, C-Term
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原理
- Rabbit Anti-Human K Cadherin (CDH6) (C-term) Antibody
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免疫原
- This K Cadherin (CDH6) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 665-695 amino acids from the C-terminal region of human K Cadherin (CDH6).
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亚型
- Ig Fraction
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应用备注
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Western Blot, Immunohistochemistry, Flow Cytometry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, FC: 1:10-50Western blot analysis of anti-DH6 Antibody (C-term) (RB14082) in 293 cell line lysates (35 μg/lane). DH6(arrow) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with CDH6 antibody (C-term) . FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- CDH6 (K-Cadherin (CDH6))
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别名
- K Cadherin
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背景
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Target Description: CDH6 is a type II classical cadherin from the cadherin superfamily. It is a calcium dependent cell-cell adhesion membrane glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of the CDH6 gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion.
Gene Symbol: CDH6
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分子量
- 88309 Da
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基因ID
- 1004
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UniProt
- P55285
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途径
- Cell-Cell Junction Organization
抗原
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