TERT 抗体 (Center)
Quick Overview for TERT 抗体 (Center) (ABIN2798432)
抗原
See all TERT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 627-656, Center
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原理
- Rabbit Anti-Human TERT (Center) Antibody
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免疫原
- This TERT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 627-656 amino acids from the Central region of human TERT.
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亚型
- Ig Fraction
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应用备注
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Western Blot, Flow Cytometry, Immunofluorescence
Recommended Dilutions
WB: 1:1000, FC: 1:10-50, IF: 1:10-50Western blot analysis of anti-TERT Antibody (Center) (RB14069) in Jurkat cell line lysates (35 μg/lane). TERT(arrow) was detected using the purified Pab.TERT Antibody (Center) . TERT immunoreactivity is localized to Nucleus significantly and Cytoplasm weakly. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 2.0 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- TERT (Telomerase Reverse Transcriptase (TERT))
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别名
- TERT
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背景
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Target Description: Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks.
Gene Symbol: TERT
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分子量
- 126997 Da
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基因ID
- 7015
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UniProt
- O14746
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途径
- Telomere Maintenance
抗原
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