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TERT 抗体 (Center)

The 兔 多克隆 anti-TERT antibody is suitable to detect TERT in samples from 人. It has been validated for WB, FACS 和 IF.
产品编号 ABIN2798432
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TERT 抗体 (Center) (ABIN2798432)

抗原

See all TERT 抗体
TERT (Telomerase Reverse Transcriptase (TERT))

适用

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宿主

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克隆类型

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多克隆

标记

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This TERT antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)
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    AA 627-656, Center

    原理

    Rabbit Anti-Human TERT (Center) Antibody

    免疫原

    This TERT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 627-656 amino acids from the Central region of human TERT.

    亚型

    Ig Fraction
  • 应用备注

    Western Blot, Flow Cytometry, Immunofluorescence
    Recommended Dilutions
    WB: 1:1000, FC: 1:10-50, IF: 1:10-50Western blot analysis of anti-TERT Antibody (Center) (RB14069) in Jurkat cell line lysates (35 μg/lane). TERT(arrow) was detected using the purified Pab.TERT Antibody (Center) . TERT immunoreactivity is localized to Nucleus significantly and Cytoplasm weakly.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2.0 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    TERT (Telomerase Reverse Transcriptase (TERT))

    别名

    TERT

    背景

    Target Description: Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks.

    Gene Symbol: TERT

    分子量

    126997 Da

    基因ID

    7015

    UniProt

    O14746

    途径

    Telomere Maintenance
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