MYBPC3 抗体 (N-Term)
Quick Overview for MYBPC3 抗体 (N-Term) (ABIN2797756)
抗原
See all MYBPC3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 189-218, N-Term
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原理
- Rabbit Anti-Mouse MYBPC3 (N-term) Antibody
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免疫原
- This MYBPC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-218 amino acids from the N-terminal region of human MYBPC3.
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亚型
- Ig Fraction
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应用备注
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50MYBPC3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.500 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))
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别名
- MYBPC3
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背景
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Target Description: MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.
Gene Symbol: MYBPC3
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分子量
- 140762 Da
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基因ID
- 4607
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UniProt
- Q14896
抗原
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