WT1 抗体 (AA 346-375)
Quick Overview for WT1 抗体 (AA 346-375) (ABIN2797552)
抗原
See all WT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 346-375
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原理
- Rabbit Anti-Human WT1 (Center E361) Antibody
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免疫原
- This WT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-375 amino acids from the Central region of human WT1.
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亚型
- Ig Fraction
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应用备注
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Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100, IF: 1:10-50, FC: 1:10-50WT1 Antibody (Center E361) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.300 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- WT1 (Wilms Tumor 1 (WT1))
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别名
- WT1
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背景
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Target Description: This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq].
Gene Symbol: WT1
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分子量
- 49188 Da
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基因ID
- 7490
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UniProt
- P19544
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途径
- Tube Formation
抗原
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