IRF9 抗体 (N-Term)
Quick Overview for IRF9 抗体 (N-Term) (ABIN2797511)
抗原
See all IRF9 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 75-104, N-Term
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原理
- Rabbit Anti-Mouse IRF9 (N-term) Antibody
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免疫原
- This IRF9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-104 amino acids from the N-terminal region of human IRF9.
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亚型
- Ig Fraction
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应用备注
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Western Blot, Immunohistochemistry, Immunofluorescence
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, IF: 1:10-50IRF9 Antibody (N-term) . -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.280 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- IRF9 (Interferon Regulatory Factor 9 (IRF9))
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别名
- IRF9
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背景
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Target Description: IRF9 is a transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Gene Symbol: IRF9
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分子量
- 43696 Da
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基因ID
- 10379
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UniProt
- Q00978
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途径
- JAK/STAT Signaling, Interferon-gamma Pathway, Hepatitis C
抗原
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