HAT1 抗体 (C-Term)
Quick Overview for HAT1 抗体 (C-Term) (ABIN2797110)
抗原
See all HAT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 389-419, C-Term
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原理
- Rabbit Anti-Human KAT1 (HAT1) (C-term) Antibody
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免疫原
- This KAT1 (HAT1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-419 amino acids from the C-terminal region of human KAT1 (HAT1).
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亚型
- Ig Fraction
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应用备注
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Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of hHAT1-E404 was detected using the purified Pab. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 2.0 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- HAT1 (Histone Aminotransferase 1 (HAT1))
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别名
- KAT1
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背景
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Target Description: Histone acetylation, particularly of histone H4, has been proposed to play an important role in replication-dependent nucleosome assembly. The HAT1 protein contains D, A, and B motifs, which are present in many N-acetyltransferases, including those that acetylate substrates other than histones. The HAT1 holoenzyme consists of 2 subunits: the catalytic 46-kD HAT1 and the accessory p46. The p46 subunit stimulated the activity of HAT1 and bound to core histones. The HAT1 holoenzyme acetylated newly synthesized but not nucleosomal histone H4 at lys5 and lys12, and, to a lesser extent, histone H2A at lys5. HAT1 and p46 polypeptides are located in the nucleus of S-phase cells. HAT1 may play a role in telomeric silencing.
Gene Symbol: HAT1
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分子量
- 49513 Da
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基因ID
- 8520
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UniProt
- O14929
抗原
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