RSPH1 抗体 (C-Term)
Quick Overview for RSPH1 抗体 (C-Term) (ABIN2796441)
抗原
See all RSPH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 532-558, C-Term
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原理
- Rabbit Anti-Human MCAM (C-term) Antibody
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免疫原
- This MCAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 532-558 amino acids from the C-terminal region of human MCAM.
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亚型
- Ig Fraction
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应用备注
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50Western blot analysis of MCAM Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.300 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- RSPH1 (Radial Spoke Head 1 Homolog (RSPH1))
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别名
- MCA
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背景
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Target Description: MCAM plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. It could be an adhesion molecule active in neural crest cells during embryonic development. It acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.
Gene Symbol: MCAM
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分子量
- 71607 Da
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基因ID
- 4162
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UniProt
- P43121
抗原
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