USP16 抗体 (Center)
Quick Overview for USP16 抗体 (Center) (ABIN2796351)
抗原
See all USP16 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 386-416, Center
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原理
- Rabbit Anti-Human USP16 (Center) Antibody
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免疫原
- This USP16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-416 amino acids from the Central region of human USP16.
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亚型
- Ig Fraction
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应用备注
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Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of anti-USP16 Pab was detected using the purified Pab. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 2.0 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- USP16 (Ubiquitin Specific Peptidase 16 (USP16))
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别名
- USP16
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背景
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Target Description: Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
Gene Symbol: USP16
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分子量
- 93570 Da
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基因ID
- 10600
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UniProt
- Q9Y5T5
抗原
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