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USP2 抗体 (N-Term)

This anti-USP2 antibody is a 兔 多克隆 antibody detecting USP2 in WB, IHC 和 ISt. Suitable for 人.
产品编号 ABIN2796342
发货至: 中国

Quick Overview for USP2 抗体 (N-Term) (ABIN2796342)

抗原

See all USP2 抗体
USP2 (Ubiquitin Specific Peptidase 2 (USP2))

适用

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宿主

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克隆类型

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多克隆

标记

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This USP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunostaining (ISt)
  • 抗原表位

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    AA 71-101, N-Term

    原理

    Rabbit Anti-Human USP2 (N-term) Antibody

    免疫原

    This USP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-101 amino acids from the N-terminal region of human USP2.

    亚型

    Ig Fraction
  • 应用备注

    Western Blot, Immunohistochemistry
    Recommended Dilutions
    WB: 1:1000, IHC: 1:10-50Western blot analysis of USP2 Antibody (N-term) with the USP2 gene.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2.0 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    USP2 (Ubiquitin Specific Peptidase 2 (USP2))

    别名

    USP2

    背景

    Target Description: Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

    Gene Symbol: USP2

    分子量

    68072 Da

    基因ID

    9099

    UniProt

    O75604
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