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NFkB 抗体 (C-Term)

This 兔 多克隆 anti-NFkB antibody specifically detects NFkB in WB. The antibody is reactive with 人 samples.
产品编号 ABIN2795621
发货至: 中国
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Quick Overview for NFkB 抗体 (C-Term) (ABIN2795621)

抗原

See all NFkB 抗体
NFkB (Nuclear Factor kappa B (NFkB))

适用

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宿主

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克隆类型

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多克隆

标记

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This NFkB antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 911-937, C-Term

    原理

    Rabbit Anti-Human NFKB(p105) (C-term S933) Antibody

    免疫原

    This NFKB(p105) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 911-937 amino acids from the C-terminal region of human NFKB(p105).

    亚型

    Ig Fraction
  • 应用备注

    Western Blot
    Recommended Dilutions
    WB: 1:1000NFKB(p105) Antibody (C-term S933) .

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.500 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    NFkB (Nuclear Factor kappa B (NFkB))

    别名

    NFKB

    背景

    Target Description: This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.

    Gene Symbol: NFKB1

    分子量

    105356 Da

    基因ID

    4790

    UniProt

    P19838

    途径

    Ubiquitin Proteasome Pathway, S100 Proteins
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