NFkB 抗体 (C-Term)
Quick Overview for NFkB 抗体 (C-Term) (ABIN2795621)
抗原
See all NFkB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 911-937, C-Term
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原理
- Rabbit Anti-Human NFKB(p105) (C-term S933) Antibody
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免疫原
- This NFKB(p105) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 911-937 amino acids from the C-terminal region of human NFKB(p105).
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亚型
- Ig Fraction
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应用备注
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Western Blot
Recommended Dilutions
WB: 1:1000NFKB(p105) Antibody (C-term S933) . -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.500 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- NFkB (Nuclear Factor kappa B (NFkB))
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别名
- NFKB
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背景
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Target Description: This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.
Gene Symbol: NFKB1
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分子量
- 105356 Da
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基因ID
- 4790
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UniProt
- P19838
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途径
- Ubiquitin Proteasome Pathway, S100 Proteins
抗原
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