DGKA 抗体 (C-Term)
Quick Overview for DGKA 抗体 (C-Term) (ABIN2793354)
抗原
See all DGKA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 598-628, C-Term
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原理
- Rabbit Anti-Human DGKA (C-term) Antibody
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免疫原
- This DGKA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 598-628 amino acids from the C-terminal region of human DGKA.
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亚型
- Ig Fraction
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应用备注
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100Western blot analysis of anti-DGKA Antibody (C-term) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. BC = breast carcinoma, HC = hepatocarcinoma. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 2.0 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- DGKA (Diacylglycerol Kinase, alpha 80kDa (DGKA))
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别名
- DGKA
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背景
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Target Description: Upon cell stimulation, the kinase DGKA converts the second messenger diacylglycerol into phophatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity. DGKA is stimulated by calcium and phosphatidylserine, and is phosphorylated by protein kinase C. Tissue expression is in lymphocytes and oligodengroglial cells. DGKA contains 2 zinc-dependent phorbol-ester and DAG binding domains, and 2 EF-hand calcium binding domains.
Gene Symbol: DGKA
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分子量
- 82630 Da
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基因ID
- 1606
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UniProt
- P23743
抗原
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