BGLF4 (AA 386-417), (C-Term) 抗体
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- 抗原
- BGLF4
- 抗原表位
- AA 386-417, C-Term
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Immunohistochemistry (IHC)
- 原理
- Rabbit Anti-Human BGLF4 (C-term) Antibody
- 免疫原
- This BGLF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-417 amino acids from the C-terminal region of human BGLF4.
- 亚型
- Ig Fraction
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- 应用备注
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Immunohistochemistry
Recommended Dilutions
IHC: 1:50-100Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. BC = breast carcinoma, HC = hepatocarcinoma. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 2.0 mg/mL
- 储存条件
- 4 °C,-20 °C
- 储存方法
- 2-8°C (short-term), -20°C (long-term)
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- 抗原
- BGLF4
- 背景
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Target Description: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
Gene Symbol: BGLF4
- 分子量
- 48351 Da
- 基因ID
- 3783704
- UniProt
- P13288
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