Transglutaminase 抗体 (AA 429-458)
Quick Overview for Transglutaminase 抗体 (AA 429-458) (ABIN2793240)
抗原
See all Transglutaminase 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 429-458
-
原理
- Rabbit Anti-Human Transglutaminase (TGM2) (Center K444) Antibody
-
免疫原
- This Transglutaminase (TGM2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 429-458 amino acids from the Central region of human Transglutaminase (TGM2).
-
亚型
- Ig Fraction
-
-
anti-Transglutaminase (AA 461-560) antibody
适用: 人, 大鼠 ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Transglutaminase (AA 429-458) antibody适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western Blot, Immunofluorescence, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IF: 1:10-50, IHC: 1:10-50TGM2 Antibody (Center K444) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 2.0 mg/mL
-
储存条件
- 4 °C,-20 °C
-
储存方法
- 2-8°C (short-term), -20°C (long-term)
-
-
- Transglutaminase
-
背景
-
Target Description: Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. It has been identified as the autoantigen implicated in celiac disease.
Gene Symbol: TGM2
-
分子量
- 77329 Da
-
基因ID
- 7052
-
UniProt
- P21980
抗原
-
