PDX1 抗体 (C-Term)
Quick Overview for PDX1 抗体 (C-Term) (ABIN2793201)
抗原
See all PDX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 186-215, C-Term
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原理
- Rabbit Anti-Human IPF (C-term) Antibody
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免疫原
- This IPF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-215 amino acids from the C-terminal region of human IPF.
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亚型
- Ig Fraction
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应用备注
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Western Blot, Immunofluorescence
Recommended Dilutions
WB: 1:1000, IF: 1:10-50Ipf Antibody (C-term) . IPF immunoreactivity is localized to Cytoplasm and Nucleus significantly. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 2.0 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
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别名
- IPF
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背景
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Target Description: IPF is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. This nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Gene Symbol: PDX1
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分子量
- 30771 Da
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基因ID
- 3651
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UniProt
- P52945
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途径
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
抗原
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