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PDGFRA 抗体 (AA 698-727)

This anti-PDGFRA antibody is a 兔 多克隆 antibody detecting PDGFRA in WB 和 IHC. Suitable for 人.
产品编号 ABIN2793153
发货至: 中国

Quick Overview for PDGFRA 抗体 (AA 698-727) (ABIN2793153)

抗原

See all PDGFRA 抗体
PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))

适用

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宿主

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克隆类型

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多克隆

标记

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This PDGFRA antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
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    AA 698-727

    原理

    Rabbit Anti-Human PDGFRA (Y720) Antibody

    免疫原

    This PDGFRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 698-727 amino acids from human PDGFRA.

    亚型

    Ig Fraction
  • 应用备注

    Western Blot, Immunohistochemistry
    Recommended Dilutions
    WB: 1:1000, IHC: 1:10-50Western blot analysis of PDGFRA (arrow) using rabbit polyclonal PDGFRA Antibody (Y720) (RB11101). 293 cell lysates (2 μg/lane) either nontransfected (Lane 1) or transiently transfected with the PDGFRA gene (Lane 2) (Origene Technologies).
    Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PDGFRA Antibody (Y720) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.300 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))

    别名

    PDGFRA

    背景

    Target Description: PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.

    Gene Symbol: PDGFRA

    分子量

    122670 Da

    基因ID

    5156

    UniProt

    P16234

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
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