Nucleobindin 1 抗体 (C-Term)
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北京 101111
Quick Overview for Nucleobindin 1 抗体 (C-Term) (ABIN2792698)
抗原
See all Nucleobindin 1 (NUCB1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- NUCB1 Antibody - C-terminal region
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序列
- PAAHPEGQLK FHPDTDDVPV PAPAGDQKEV DTSEKKLLER LPEVEVPQHL
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交叉反应
- 人
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预测反应
- Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against NUCB1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human NUCB1
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anti-Nucleobindin 1 (NUCB1) (AA 28-461) antibody
NUCB1 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1H8-2C11 unconjugated
anti-Nucleobindin 1 (NUCB1) (AA 302-461) antibodyNUCB1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nucleobindin 1 (NUCB1) (C-Term) antibodyNUCB1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nucleobindin 1 (NUCB1) (AA 1-461) antibodyNUCB1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Nucleobindin 1 (NUCB1) (AA 26-413) antibodyNUCB1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nucleobindin 1 (NUCB1) (C-Term) antibodyNUCB1 适用: 小鼠, 大鼠, 犬 IHC 宿主: 兔 Polyclonal unconjugated
anti-Nucleobindin 1 (NUCB1) (C-Term) antibodyNUCB1 适用: 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nucleobindin 1 (NUCB1) (AA 411-461) antibodyNUCB1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Nucleobindin 1 (NUCB1) (C-Term) antibodyNUCB1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nucleobindin 1 (NUCB1) (C-Term) antibodyNUCB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Nucleobindin 1 binds to multiple types of pre-fibrillar amyloid and inhibits fibrillization." in: Scientific reports, Vol. 7, pp. 42880, (2017) (PubMed).
: "Topology and membrane anchoring of the lysosomal storage disease-related protein CLN5." in: Human mutation, Vol. 34, Issue 12, pp. 1688-97, (2013) (PubMed).
: "Calnuc plays a role in dynamic distribution of Galphai but not Gbeta subunits and modulates ACTH secretion in AtT-20 neuroendocrine secretory cells." in: Molecular neurodegeneration, Vol. 4, pp. 15, (2009) (PubMed).
: "Modulation of nucleobindin-1 and nucleobindin-2 by caspases." in: FEBS letters, Vol. 582, Issue 2, pp. 286-90, (2008) (PubMed).
: "Serine 129 phosphorylation of alpha-synuclein induces unfolded protein response-mediated cell death." in: The Journal of biological chemistry, Vol. 283, Issue 34, pp. 23179-88, (2008) (PubMed).
: "Calnuc binds to Alzheimer's beta-amyloid precursor protein and affects its biogenesis." in: Journal of neurochemistry, Vol. 100, Issue 6, pp. 1505-14, (2007) (PubMed).
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- Nucleobindin 1 (NUCB1)
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别名
- NUCB1
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背景
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Background Information: Nucleobindin, also known as calnuc, participates in Ca2+ storage in the Golgi, as well as in other biological processes that involve DNA-binding and protein-protein interactions.
Gene Name: Nucleobindin 1
Alternative Symbols: NUC, CALNUC
Protein Name: Nucleobindin-1
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分子量
- 54kDa
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基因ID
- 4924
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NCBI登录号
- NP_006175
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UniProt
- Q02818
抗原
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