Nucleobindin 1 抗体 (C-Term)
(6 references)Quick Overview for Nucleobindin 1 抗体 (C-Term) (ABIN2792698)
抗原
See all Nucleobindin 1 (NUCB1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
序列
- PAAHPEGQLK FHPDTDDVPV PAPAGDQKEV DTSEKKLLER LPEVEVPQHL
-
交叉反应
- 人
-
预测反应
- Human: 100%
-
产品特性
- This is a rabbit polyclonal antibody against NUCB1. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human NUCB1
-
-
anti-Nucleobindin 1 (NUCB1) (AA 28-461) antibody
NUCB1 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1H8-2C11 unconjugated
anti-Nucleobindin 1 (NUCB1) (AA 302-461) antibodyNUCB1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nucleobindin 1 (NUCB1) (C-Term) antibodyNUCB1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nucleobindin 1 (NUCB1) (AA 1-461) antibodyNUCB1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Nucleobindin 1 (NUCB1) (AA 26-413) antibodyNUCB1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nucleobindin 1 (NUCB1) (C-Term) antibodyNUCB1 适用: 小鼠, 大鼠, 犬 IHC 宿主: 兔 Polyclonal unconjugated
anti-Nucleobindin 1 (NUCB1) (AA 1-461) antibodyNUCB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Nucleobindin 1 (NUCB1) (C-Term) antibodyNUCB1 适用: 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nucleobindin 1 (NUCB1) (C-Term) antibodyNUCB1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nucleobindin 1 (NUCB1) (C-Term) antibodyNUCB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
WB Suggested Anti-NUCB1 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. -
说明
-
Antigen size: 461 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
-
: "Nucleobindin 1 binds to multiple types of pre-fibrillar amyloid and inhibits fibrillization." in: Scientific reports, Vol. 7, pp. 42880, (2017) (PubMed).
: "Topology and membrane anchoring of the lysosomal storage disease-related protein CLN5." in: Human mutation, Vol. 34, Issue 12, pp. 1688-97, (2013) (PubMed).
: "Calnuc plays a role in dynamic distribution of Galphai but not Gbeta subunits and modulates ACTH secretion in AtT-20 neuroendocrine secretory cells." in: Molecular neurodegeneration, Vol. 4, pp. 15, (2009) (PubMed).
: "Modulation of nucleobindin-1 and nucleobindin-2 by caspases." in: FEBS letters, Vol. 582, Issue 2, pp. 286-90, (2008) (PubMed).
: "Serine 129 phosphorylation of alpha-synuclein induces unfolded protein response-mediated cell death." in: The Journal of biological chemistry, Vol. 283, Issue 34, pp. 23179-88, (2008) (PubMed).
: "Calnuc binds to Alzheimer's beta-amyloid precursor protein and affects its biogenesis." in: Journal of neurochemistry, Vol. 100, Issue 6, pp. 1505-14, (2007) (PubMed).
-
: "Nucleobindin 1 binds to multiple types of pre-fibrillar amyloid and inhibits fibrillization." in: Scientific reports, Vol. 7, pp. 42880, (2017) (PubMed).
-
- Nucleobindin 1 (NUCB1)
-
别名
- Nucleobindin-1
-
背景
-
Nucleobindin, also known as calnuc, participates in Ca2+ storage in the Golgi, as well as in other biological processes that involve DNA-binding and protein-protein interactions.
Alias Symbols: NUC, CALNUC
Protein Interaction Partner: REL, UBC, MDM2, CTPS2, RAD23B, PRKDC, METTL1, GTF2I, CBS, XPNPEP1, WARS, PTGS2, XPO1, SET, RBL1, MYC, HIVEP1, GNAS, GNAI3, GNAI1, KLC4, PTGS1, NDN, GNAI2, GNAO1, GNAZ,
Protein Size: 461 -
分子量
- 54 kDa
-
基因ID
- 4924
-
NCBI登录号
- NM_006184, NP_006175
-
UniProt
- Q02818
抗原
-
