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Caveolin-1 抗体 (N-Term)

CAV1 适用: 人, 大鼠, 小鼠, 犬, Pig, 兔, Cow, 绵羊, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2792696
发货至: 中国
  • 抗原 See all Caveolin-1 (CAV1) 抗体
    Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))
    抗原表位
    • 15
    • 14
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 107
    • 63
    • 49
    • 10
    • 9
    • 8
    • 8
    • 8
    • 8
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠, 犬, Pig, 兔, Cow, 绵羊, 马
    宿主
    • 98
    • 12
    • 6
    • 2
    克隆类型
    • 93
    • 25
    多克隆
    标记
    • 82
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Caveolin-1 antibody is un-conjugated
    应用范围
    • 92
    • 38
    • 27
    • 27
    • 26
    • 17
    • 16
    • 16
    • 11
    • 11
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    SGGKYVDSEG HLYTVPIREQ GNIYKPNNKA MADELSEKQV YDAHTKEIDL
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Cow: 80%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 80%, Rabbit: 86%, Rat: 86%, Sheep: 80%
    产品特性
    This is a rabbit polyclonal antibody against CAV1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human CAV1
    Top Product
    Discover our top product CAV1 Primary Antibody
  • 应用备注
    WB Suggested Anti-CAV1 Antibody Titration: 0.2-1 µg/mL
    ELISA Titer: 1:62500
    Positive Control: Human Liver.
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 178 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))
    别名
    Caveolin-1 (CAV1 产品)
    别名
    fc07c04 antibody, wu:fc07c04 antibody, Cav-1 antibody, bscl3 antibody, cav1 antibody, cav1a antibody, cgl3 antibody, vip21 antibody, cav1b antibody, caveolin-1 antibody, cav antibody, mstp085 antibody, Caveolin-1 antibody, CAV1 antibody, cav-1 antibody, Cav antibody, caveolin 1 antibody, BSCL3 antibody, CGL3 antibody, MSTP085 antibody, PPH3 antibody, VIP21 antibody, caveolin 1 antibody, caveolin 1 L homeolog antibody, caveolin 1 S homeolog antibody, caveolin 1, caveolae protein antibody, caveolin 1, caveolae protein, 22kDa antibody, Caveolin antibody, cav1 antibody, cav1.L antibody, cav1.S antibody, CAV1 antibody, Cav1 antibody, cav-1 antibody
    背景
    The scaffolding protein CAV1 is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene.The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CAV, MSTP085, VIP21, CGL3, BSCL3
    Protein Interaction Partner: TFRC, ABCC1, UBC, RPA3, ATG5, ATG12, RPA2, RPA1, PTGIS, EGFR, VCP, UFD1L, PTGS2, PTGS1, ESR1, DERL1, VIMP, ATP4A, CAV2, GLIPR2, KDR, PROCR, F2R, BID, NOS3, HSP90AA1, FAS, ACTB, MALL, NF1, LRP6, KCNMA1, BMPR2, BMPR1A, AXIN1, PPP2CA, MCL1, ITPR3, ID1, TENC1
    Protein Size: 178
    分子量
    20 kDa
    基因ID
    857
    NCBI登录号
    NM_001753, NP_001744
    UniProt
    Q03135
    途径
    Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals
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