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Cyclin H 抗体 (Middle Region)

CCNH 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, 马, Cow WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2792693
发货至: 中国
  • 抗原 See all Cyclin H (CCNH) 抗体
    Cyclin H (CCNH)
    抗原表位
    • 13
    • 12
    • 10
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 88
    • 46
    • 27
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, 豚鼠, 兔, 马, Cow
    宿主
    • 76
    • 14
    克隆类型
    • 69
    • 21
    多克隆
    标记
    • 50
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This Cyclin H antibody is un-conjugated
    应用范围
    • 59
    • 37
    • 23
    • 21
    • 16
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    KQKLERCHSA ELALNVITKK RKGYEDDDYV SKKSKHEEEE WTDDDLVESL
    交叉反应
    牛, 人, 小鼠, 猪, 大鼠
    预测反应
    Cow: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 85%, Rabbit: 78%, Rat: 85%
    产品特性
    This is a rabbit polyclonal antibody against CCNH. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human CCNH
    Top Product
    Discover our top product CCNH Primary Antibody
  • 应用备注
    WB Suggested Anti-CCNH Antibody Titration: 0.2-1 µg/mL
    ELISA Titer: 1:1562500
    Positive Control: MCF7 cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 323 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Cyclin H (CCNH)
    别名
    Cyclin H (CCNH 产品)
    别名
    zgc:114132 antibody, cak antibody, p34 antibody, p37 antibody, Cych antibody, ACYPI004637 antibody, ccnh antibody, Cyclin-H antibody, 142767_at antibody, CG7405 antibody, Dmel\\CG7405 antibody, CAK antibody, 6330408H09Rik antibody, AI661354 antibody, AV102684 antibody, AW538719 antibody, ccnh-A antibody, cyclin H antibody, cyclin-H antibody, Cyclin H antibody, CYclin H antibody, cyclin H L homeolog antibody, CCNH antibody, ccnh antibody, LOC5577539 antibody, Cych antibody, CycH antibody, cyh-1 antibody, Ccnh antibody, ccnh.L antibody
    背景
    CCNH belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery.The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CAK, p34, p37
    Protein Interaction Partner: SFN, GOLGA2, SSX2IP, CCDC170, CCDC33, DUSP12, SSSCA1, NDC80, CALCOCO2, PPFIA1, PSMA1, KLC3, RPA3, RPA2, RPA1, NEDD4, CDK7, CDK8, CDK2, CCNC, MNAT1, MBP, CTD, CDK20, CTBP2, CSNK2B, TRIM8, GANAB, RARB, POLR2A, GTF2H4, ERCC2, tat, POLR2B, CDK9, BRCA1, GTF2H1
    Protein Size: 323
    分子量
    38 kDa
    基因ID
    902
    NCBI登录号
    NM_001239, NP_001230
    UniProt
    P51946
    途径
    Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
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