Cyclin H 抗体 (Middle Region)
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北京 101111
Quick Overview for Cyclin H 抗体 (Middle Region) (ABIN2792693)
抗原
See all Cyclin H (CCNH) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- CCNH Antibody - middle region
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序列
- KQKLERCHSA ELALNVITKK RKGYEDDDYV SKKSKHEEEE WTDDDLVESL
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交叉反应
- 牛, 人, 小鼠, 猪, 大鼠
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预测反应
- Cow: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 85%, Rabbit: 78%, Rat: 85%
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产品特性
- This is a rabbit polyclonal antibody against CCNH. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CCNH
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anti-Cyclin H (CCNH) (AA 1-110) antibody
CCNH 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1B8 unconjugated
anti-Cyclin H (CCNH) (AA 1-323) antibodyCCNH 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Cyclin H (CCNH) antibodyCCNH 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Cyclin H (CCNH) (AA 269-299), (C-Term) antibodyCCNH 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB14888 unconjugated
anti-Cyclin H (CCNH) (pThr315) antibodyCCNH 适用: 人, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin H (CCNH) (AA 1-323) antibodyCCNH 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Cyclin H (CCNH) (AA 221-323) antibodyCCNH 适用: 人 WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin H (CCNH) antibodyCCNH 适用: 人 WB, IP 宿主: 小鼠 Monoclonal unconjugated
anti-Cyclin H (CCNH) (AA 24-52), (N-Term) antibodyCCNH 适用: 小鼠 WB, FACS 宿主: 兔 Polyclonal RB14999 unconjugated
anti-Cyclin H (CCNH) (C-Term) antibodyCCNH 适用: 人, 小鼠, 大鼠, Pig, 豚鼠, 兔, 马, Cow, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Cyclin H (CCNH)
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别名
- CCNH
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背景
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Background Information: CCNH belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery.The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gene Name: Cyclin H
Alternative Symbols: CAK, p34, p37, CycH
Protein Name: Cyclin-H
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分子量
- 38kDa
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基因ID
- 902
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NCBI登录号
- NP_001230
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UniProt
- P51946
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
抗原
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