SUB1 抗体 (Middle Region)
Quick Overview for SUB1 抗体 (Middle Region) (ABIN2792675)
抗原
See all SUB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- NMFQIGKMRY VSVRDFKGKV LIDIREYWMD PEGEMKPGRK GISLNPEQWS
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交叉反应
- 牛, 犬, 小鸡, 人, 小鼠, 大鼠
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预测反应
- Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against PC4. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PC4
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anti-Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1) (AA 1-127) antibody
SUB1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1) antibodySUB1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1) (AA 32-124) antibodySUB1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A1 unconjugated
anti-Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1) (AA 96-127), (C-Term) antibodySUB1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1) (AA 2-127) antibodySUB1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1) (AA 1-127) antibodySUB1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1) (AA 62-111) antibodySUB1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 斑马鱼, 豚鼠, Pig, Saccharomyces cerevisiae, 小鸡, 兔, 猴, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1) (N-Term) antibodySUB1 适用: 人, Cow, 犬, 马, 豚鼠, Pig, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1) antibodySUB1 适用: 人, 小鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1) (AA 96-127) antibodySUB1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB Suggested Anti-PC4 Antibody Titration: 0.5-1.0 µg/mL
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. -
说明
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Antigen size: 127 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SUB1 (Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1))
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别名
- SUB1 / PC4
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背景
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PC4 (activated RNA polymerase II transcription cofactor 4) is a transcriptional coactivator, possessing the ability to suppress promoter-driven as well as nonspecific transcription via its DNA binding activity. The repressive activity of PC4 on promoter-driven transcription is alleviated by transcription factor TFIIH. TFIIH protects promoters from PC4-mediated repression by relieving the topological constraint imposed by PC4 through the ERCC3 helicase activity.
Alias Symbols: P15, PC4, p14
Protein Interaction Partner: HUWE1, SUB1, UBC, rev, CLK4, CDK2, HNF4A, FN1, CSNK2A1, SMURF1, RPL18A, LAMP2, CDC5L, APP, YWHAZ, GTF3C1, ELAVL1, SUMO2, HDGF, Shoc2, Kif1c, POLR2B, POLR2A, CBX5, RCOR1, REST, BANF1, ADAP1, GTF2A1L, EP300, POU2AF1, CSTF2, TBP, TAF1, PCNA, HSF1, PSIP1, SP1
Protein Size: 127 -
分子量
- 14 kDa
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基因ID
- 10923
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NCBI登录号
- NM_006713, NP_006704
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UniProt
- P53999
抗原
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