LMO2 抗体 (N-Term)
Quick Overview for LMO2 抗体 (N-Term) (ABIN2792668)
抗原
See all LMO2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- GGGARAPEGV RAPAAGQPRA TKGAPPPPGT PPPSPMSSAI ERKSLDPSEE
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交叉反应
- 牛, 小鸡, 人, 小鼠, 大鼠
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预测反应
- Dog: 100%, Guinea Pig: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against LMO2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human LMO2
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应用备注
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WB Suggested Anti-LMO2 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: Human kidney.
Optimal working dilutions should be determined experimentally by the investigator. -
说明
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Antigen size: 158 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))
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别名
- Rhombotin-2
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背景
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LMO2 acts with TAL1/SCL to regulate red blood cell development. LMO2 also acts with LDB1 to maintain erythroid precursors in an immature state.LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: RBTN2, RBTNL1, RHOM2, TTG2
Protein Interaction Partner: ADAMTSL4, MBIP, HOOK1, TFPT, NOTCH2NL, KRTAP10-7, CCDC36, NUTM1, SPERT, FAM154A, CLHC1, KRT40, SSX2IP, CMTM5, MRFAP1L1, IFT43, C1orf94, LZTS2, TSC22D4, DBF4B, CCDC33, RINT1, NIF3L1, TRIM54, AGTRAP, ZFP64, BANP, STAT3, STAT1, SOX5, SKP1, ROCK1, REL, PRKG1,
Protein Size: 158 -
分子量
- 18 kDa
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基因ID
- 4005
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NCBI登录号
- NM_005574, NP_005565
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UniProt
- P25791
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途径
- Chromatin Binding
抗原
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