EN1 抗体 (C-Term)
(1 reference)Quick Overview for EN1 抗体 (C-Term) (ABIN2792656)
抗原
See all EN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- LMGSANGGPV VKTDSQQPLV WPAWVYCTRY SDRPSSGPRT RKLKKKKNEK
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交叉反应
- 小鸡, 人, 小鼠
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预测反应
- Guinea Pig: 93%, Rabbit: 86%
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产品特性
- This is a rabbit polyclonal antibody against EN1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human EN1
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anti-Engrailed Homeobox 1 (EN1) (AA 1-30), (N-Term) antibody
EN1 适用: 人, 小鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal RB13885 unconjugated
anti-Engrailed Homeobox 1 (EN1) (AA 266-392) antibodyEN1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3H2 unconjugated
anti-Engrailed Homeobox 1 (EN1) antibodyEN1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Engrailed Homeobox 1 (EN1) (C-Term) antibodyEN1 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, Cow, 犬, 马, 猴, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Engrailed Homeobox 1 (EN1) (AA 252-301) antibodyEN1 适用: 人, 小鼠, 小鸡, 大鼠, 豚鼠, Cow, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Engrailed Homeobox 1 (EN1) (C-Term) antibodyEN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB Suggested Anti-EN1 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. -
说明
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Antigen size: 392 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Novel role of Engrailed 1 as a prosurvival transcription factor in basal-like breast cancer and engineering of interference peptides block its oncogenic function." in: Oncogene, Vol. 33, Issue 39, pp. 4767-77, (2014) (PubMed).
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: "Novel role of Engrailed 1 as a prosurvival transcription factor in basal-like breast cancer and engineering of interference peptides block its oncogenic function." in: Oncogene, Vol. 33, Issue 39, pp. 4767-77, (2014) (PubMed).
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- EN1 (Engrailed Homeobox 1 (EN1))
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别名
- Engrailed-1 / EN1
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背景
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Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: TLE1, PAX6, JUN,
Protein Size: 392 -
分子量
- 40 kDa
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基因ID
- 2019
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NCBI登录号
- NM_001426, NP_001417
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UniProt
- Q05925
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途径
- Dopaminergic Neurogenesis
抗原
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