NFKBIL2 抗体 (Middle Region)
(1 reference)Quick Overview for NFKBIL2 抗体 (Middle Region) (ABIN2792627)
抗原
See all NFKBIL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- RAIIHVSLAT TLGDMKDHHG AVRHYEEELR LRSGNVLEEA KTWLNIALSR
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交叉反应
- 犬, 人, 小鼠, 大鼠
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预测反应
- Dog: 84%, Human: 100%, Mouse: 83%, Rat: 83%
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产品特性
- This is a rabbit polyclonal antibody against NFKBIL2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human NFKBIL2
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anti-Tonsoku-Like, DNA Repair Protein (NFKBIL2) antibody
NFKBIL2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tonsoku-Like, DNA Repair Protein (NFKBIL2) (AA 160-390) antibodyNFKBIL2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tonsoku-Like, DNA Repair Protein (NFKBIL2) (AA 668-955) antibodyNFKBIL2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Tonsoku-Like, DNA Repair Protein (NFKBIL2) (AA 1-97) antibodyNFKBIL2 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tonsoku-Like, DNA Repair Protein (NFKBIL2) (AA 1-1219) antibodyNFKBIL2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tonsoku-Like, DNA Repair Protein (NFKBIL2) (AA 1-1219) antibodyNFKBIL2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tonsoku-Like, DNA Repair Protein (NFKBIL2) (AA 351-400) antibodyNFKBIL2 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Tonsoku-Like, DNA Repair Protein (NFKBIL2) antibodyNFKBIL2 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tonsoku-Like, DNA Repair Protein (NFKBIL2) antibodyNFKBIL2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB Suggested Anti-NFKBIL2 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:62500
Positive Control: 293T cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. -
说明
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Antigen size: 1219 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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- NFKBIL2 (Tonsoku-Like, DNA Repair Protein (NFKBIL2))
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别名
- NFKBIL2 / IKBR
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背景
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NFKBIL2 is thought to be a negative regulator of NF-kappa-B mediated transcription. It may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.
Alias Symbols: FLJ40087, IKBR, NFKBIL2
Protein Interaction Partner: HIST3H3, MCM6, MCM2, MMS22L, ASF1B, ASF1A, UBC, MYC, MAU2, SLC25A5, SUPT16H, SUGT1, AIFM1, HIST1H2BL, XRCC5, SSRP1, SLC25A3, TONSL, MCM4, HIST1H2AE, HIST1H1B, HIST1H1C, XRCC6, GSK3B, MCM7, MCM5, MCM3, EWSR1,
Protein Size: 1219 -
分子量
- 133 kDa
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基因ID
- 4796
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NCBI登录号
- NM_013432, NP_038460
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UniProt
- Q96HA7
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途径
- Maintenance of Protein Location
抗原
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