电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

Retinoic Acid Receptor alpha 抗体 (Middle Region)

RARA 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2792621
发货至: 中国
  • 抗原 See all Retinoic Acid Receptor alpha (RARA) 抗体
    Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))
    抗原表位
    • 15
    • 11
    • 11
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 88
    • 38
    • 37
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 兔
    宿主
    • 74
    • 17
    • 1
    克隆类型
    • 67
    • 25
    多克隆
    标记
    • 52
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Retinoic Acid Receptor alpha antibody is un-conjugated
    应用范围
    • 60
    • 41
    • 37
    • 21
    • 15
    • 13
    • 13
    • 11
    • 11
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    EMLENSEGLD TLSGQPGGGG RDGGGLAPPP GSCSPSLSPS SNRSSPATHS
    交叉反应
    犬, 小鸡, 人, 小鼠, 大鼠
    预测反应
    Cow: 100%, Dog: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 85%
    产品特性
    This is a rabbit polyclonal antibody against RARA. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human RARA
    Top Product
    Discover our top product RARA Primary Antibody
  • 应用备注
    WB Suggested Anti-RARA Antibody Titration: 0.2-1 µg/mL
    ELISA Titer: 1:312500
    Positive Control: OVCAR-3 cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 462 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))
    别名
    RAR-alpha / RARA (RARA 产品)
    别名
    NR1B1 antibody, RAR antibody, Nr1b1 antibody, RARalpha1 antibody, rar-alpha antibody, etID309833.12 antibody, rara antibody, rara2a antibody, zRAR antibody, zRAR-alpha antibody, zgc:109797 antibody, nr1b1 antibody, RAR-ALPHA1 antibody, HS-RARa antibody, fj66e06 antibody, rara2b antibody, wu:fj66e06 antibody, retinoic acid receptor alpha antibody, retinoic acid receptor, alpha antibody, retinoic acid receptor, alpha a antibody, retinoic acid receptor alpha L homeolog antibody, retinoic acid receptor, alpha b antibody, RARA antibody, Rara antibody, LOC100136372 antibody, raraa antibody, rara.L antibody, rara antibody, rarab antibody
    背景
    Retinoid signaling is transduced by 2 families of nuclear receptors, retinoic acid receptor (RAR) and retinoid X receptor, which form RXR/RAR heterodimers. In the absence of ligand, DNA-bound RXR/RARA represses transcription by recruiting the corepressors NCOR1, SMRT, and histone deacetylase. When ligand binds to the complex, it induces a conformational change allowing the recruitment of coactivators, histone acetyltransferases, and the basic transcription machinery.
    Alias Symbols: NR1B1, RAR
    Protein Interaction Partner: NCOR2, NCOR1, RXRG, MED1, HDAC1, NRIP1, TEKT4, NSD1, NCOA1, CEBPA, ITGB1BP2, SUMO1, UBC, MBD3, CBX5, MTA2, E2F1, WWOX, Sumo2, RXRB, RXRA, AKT1, MMS19, Dlg4, TMEM54, FN1, USP7, NCOA2, SUZ12, EZH2, PML, PSMC5, FAS, PRAM1, TBL1XR1, PRAME, ARID5A, UBE3A, UBQL
    Protein Size: 462
    分子量
    51 kDa
    基因ID
    5914
    NCBI登录号
    NM_000964, NP_000955
    UniProt
    P10276
    途径
    Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, S100 Proteins
You are here:
客服