Retinoic Acid Receptor alpha 抗体 (Middle Region)
Quick Overview for Retinoic Acid Receptor alpha 抗体 (Middle Region) (ABIN2792621)
抗原
See all Retinoic Acid Receptor alpha (RARA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- EMLENSEGLD TLSGQPGGGG RDGGGLAPPP GSCSPSLSPS SNRSSPATHS
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交叉反应
- 犬, 小鸡, 人, 小鼠, 大鼠
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预测反应
- Cow: 100%, Dog: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 85%
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产品特性
- This is a rabbit polyclonal antibody against RARA. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human RARA
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anti-Retinoic Acid Receptor, alpha (RARA) (AA 68-173) antibody
RARA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (AA 315-424) antibodyRARA 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2D2 unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (AA 1-457) antibodyRARA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (AA 237-459) antibodyRARA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (AA 315-424) antibodyRARA 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1C10 unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (AA 1-462) antibodyRARA 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2C9-1F8 unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (N-Term) antibodyRARA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (AA 322-349), (C-Term) antibodyRARA 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB33783 unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (pSer77) antibodyRARA 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Retinoic Acid Receptor, alpha (RARA) (AA 315-424) antibodyRARA 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C3 unconjugated
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应用备注
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WB Suggested Anti-RARA Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:312500
Positive Control: OVCAR-3 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. -
说明
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Antigen size: 462 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))
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别名
- RAR-alpha / RARA
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背景
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Retinoid signaling is transduced by 2 families of nuclear receptors, retinoic acid receptor (RAR) and retinoid X receptor, which form RXR/RAR heterodimers. In the absence of ligand, DNA-bound RXR/RARA represses transcription by recruiting the corepressors NCOR1, SMRT, and histone deacetylase. When ligand binds to the complex, it induces a conformational change allowing the recruitment of coactivators, histone acetyltransferases, and the basic transcription machinery.
Alias Symbols: NR1B1, RAR
Protein Interaction Partner: NCOR2, NCOR1, RXRG, MED1, HDAC1, NRIP1, TEKT4, NSD1, NCOA1, CEBPA, ITGB1BP2, SUMO1, UBC, MBD3, CBX5, MTA2, E2F1, WWOX, Sumo2, RXRB, RXRA, AKT1, MMS19, Dlg4, TMEM54, FN1, USP7, NCOA2, SUZ12, EZH2, PML, PSMC5, FAS, PRAM1, TBL1XR1, PRAME, ARID5A, UBE3A, UBQL
Protein Size: 462 -
分子量
- 51 kDa
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基因ID
- 5914
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NCBI登录号
- NM_000964, NP_000955
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UniProt
- P10276
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途径
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, S100 Proteins
抗原
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