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IRF8 抗体 (N-Term)

This 兔 多克隆 anti-IRF8 antibody specifically detects IRF8 in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 和 斑马鱼 samples.
产品编号 ABIN2792611
发货至: 中国
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Quick Overview for IRF8 抗体 (N-Term) (ABIN2792611)

抗原

See all IRF8 抗体
IRF8 (Interferon Regulatory Factor 8 (IRF8))

适用

  • 36
  • 22
  • 12
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
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人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼

宿主

  • 44
  • 2
  • 1

克隆类型

  • 36
  • 11
多克隆

标记

  • 34
  • 2
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  • 1
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This IRF8 antibody is un-conjugated

应用范围

  • 36
  • 20
  • 16
  • 15
  • 7
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    MFRIPWKHAG KQDYNQEVDA SIFKAWAVFK GKFKEGDKAE PATWKTRLRC

    交叉反应

    牛, 犬, 小鸡, 人, 小鼠, 大鼠

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against IRF8. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human IRF8
  • 应用备注

    WB Suggested Anti-IRF8 Antibody Titration: 0.2-1 µg/mL
    ELISA Titer: 1:62500
    Positive Control: Jurkat cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 426 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    IRF8 (Interferon Regulatory Factor 8 (IRF8))

    别名

    IRF8 / ICSBP1

    背景

    Interferon regulatory factor 8 (IRF8, interferon consensus sequence-binding protein, Ion ChannelSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-. and IFN-.. IRF family proteins also control expression of IFN-. and IFN-.-regulated genes that are induced by viral infection.
    Alias Symbols: ICSBP, IRF-8, ICSBP1, H-ICSBP
    Protein Interaction Partner: SPI1, IRF1, TOP1, ZBTB17, PDGFRB, CBL, UBC, COPS4, COPS5, COPS6, COPS2, MID1, IRF6, GPS1, CDK4, SQSTM1, TRAF6, SMURF2, IRF2, TRIM21, IRF8, ETV6, RELA, NFKB1,
    Protein Size: 426

    分子量

    48 kDa

    基因ID

    3394

    NCBI登录号

    NM_002163, NP_002154

    UniProt

    Q02556

    途径

    Cellular Response to Molecule of Bacterial Origin
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