GATA1 抗体 (N-Term)
Quick Overview for GATA1 抗体 (N-Term) (ABIN2792607)
抗原
See all GATA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- SGPEGLDAAA SSTAPSTATA AAAALAYYRD AEAYRHSPVF QVYPLLNCME
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交叉反应
- 牛, 犬, 人, 小鼠, 大鼠
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%, Sheep: 100%
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产品特性
- This is a rabbit polyclonal antibody against GATA1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human GATA1
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应用备注
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WB Suggested Anti-GATA1 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:312500
Positive Control: MCF7 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. -
说明
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Antigen size: 413 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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GATA-1 binding sites in exon 1 direct erythroid-specific transcription of PPOX." in: Gene, Vol. 409, Issue 1-2, pp. 83-91, (2008) (PubMed).
: "
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GATA-1 binding sites in exon 1 direct erythroid-specific transcription of PPOX." in: Gene, Vol. 409, Issue 1-2, pp. 83-91, (2008) (PubMed).
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- GATA1 (GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))
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别名
- GATA1
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背景
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GATA1 is a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ERYF1, GF1, NFE1, GF-1, XLTT, GATA-1
Protein Interaction Partner: KRTAP10-5, CCDC24, HEXIM2, FBF1, KRTAP9-2, RADIL, FRS3, PRKAB2, HSPB1, HOXA1, AKT1, SPIB, SPI1, PRKAA1, HSPA4, FLI1, CASP3, SRA1, SUMO1, CEBPE, MAPK6, UBC, SKI, NME1, RAI1, ZBTB22, TRIM25, TAF7, TAX1BP3, ZZZ3, TRIM29, IKZF1, Rb1, ZFPM1, ZNF521, ZBTB16, HD
Protein Size: 413 -
分子量
- 43 kDa
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基因ID
- 2623
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NCBI登录号
- NM_002049, NP_002040
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UniProt
- P15976
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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