RUNX1 抗体 (Middle Region)
Quick Overview for RUNX1 抗体 (Middle Region) (ABIN2792598)
抗原
See all RUNX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- ASLNHSTAFN PQPQSQMQDT RQIQPSPPWS YDQSYQYLGS IASPSVHPAT
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交叉反应
- 牛, 犬, 人, 小鼠, 大鼠
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预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against RUNX1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human RUNX1
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anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 210-310) antibody
RUNX1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2C10 unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 150-250) antibodyRUNX1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 221-480) antibodyRUNX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) antibodyRUNX1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 210-310) antibodyRUNX1 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 3A1 unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (pSer304) antibodyRUNX1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 227-255) antibodyRUNX1 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 237-337) antibodyRUNX1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 6C12A5 unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) antibodyRUNX1 适用: 人 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 5A1 unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 200-233), (Middle Region) antibodyRUNX1 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB Suggested Anti-RUNX1 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: SH-SYSY cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. -
说明
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Antigen size: 480 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))
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别名
- RUNX1
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背景
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Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. RUNX1 is the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with severaltypes of leukemia. Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AML1, AML1-EVI-1, AMLCR1, CBFA2, EVI-1, PEBP2aB
Protein Interaction Partner: YAP1, UBC, HDAC11, SOX2, SMAD3, CTBP1, RUNX1, FOXP3, NCOR2, MYC, NOTCH1, UXT, CTBP2, KAT6A, PML, CREBBP, CBFB, PRMT1, HLA-DMA, HDAC2, HDAC1, CBFA2T3, RUNX1T1, CBFA2T2, ELAVL1, DNMT1, SPEN, RBM14, KMT2A, COPRS, HDAC3, TAL1, CDK1, SMARCC1, SMARCB1, SMARCA4,
Protein Size: 480 -
分子量
- 52 kDa
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基因ID
- 861
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NCBI登录号
- NM_001754, NP_001745
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UniProt
- B2RMS4
抗原
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