NR2C1 抗体 (C-Term)
Quick Overview for NR2C1 抗体 (C-Term) (ABIN2792596)
抗原
See all NR2C1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- QEKAYVEFQD YITKTYPDDT YRLSRLLLRL PALRLMNATI TEELFFKGLI
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交叉反应
- 牛, 犬, 小鸡, 人, 小鼠, 大鼠
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 92%
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产品特性
- This is a rabbit polyclonal antibody against NR2C1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human NR2C1
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anti-Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) (N-Term) antibody
NR2C1 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Pig, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) (AA 1-240) antibodyNR2C1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) (AA 1-240) antibodyNR2C1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) antibodyNR2C1 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) (AA 1-467) antibodyNR2C1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) (N-Term) antibodyNR2C1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) (C-Term) antibodyNR2C1 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, 兔, Pig, 斑马鱼, 猴, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) (AA 1-240) antibodyNR2C1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) (AA 17-124) antibodyNR2C1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) antibodyNR2C1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB Suggested Anti-NR2C1 Antibody Titration: 2.5 µg/mL
ELISA Titer: 1:312500
Positive Control: HCT15 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. -
说明
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Antigen size: 603 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))
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别名
- NR2C1
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背景
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The nuclear orphan receptors NR2C1 represses transcription and binds DNA as a homodimer. NR2C1 binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. NR2C1 may function as a negative modulator to suppress androgen receptor function in prostate cancer. NR2C1 may exert an important repressor in regulating ER activity in mammary glands. The nuclear orphan receptors TR2 (NR2C1) and TR4 form a heterodimer that binds to the epsilon and gamma globin promoter DR1 sites
Alias Symbols: TR2
Protein Interaction Partner: PSPC1, MBD3, SIN3A, RCOR1, KDM1A, POLD3, TRIM28, RBM39, MTA2, MTA1, HDAC3, NR2C2, SMARCA4, SFPQ, RBBP7, RBBP4, NONO, HDAC2, HDAC1, HCFC1, DNMT1, CHD4, NUDT3, UBC, PML, HDAC4, NRIP1, AR, ESR1,
Protein Size: 603 -
分子量
- 67 kDa
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基因ID
- 7181
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NCBI登录号
- NM_003297, NP_003288
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UniProt
- Q15625
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途径
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
抗原
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