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ETV6 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects ETV6 in WB 和 IHC. It exhibits reactivity toward 人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, 马, 兔 和 豚鼠.
产品编号 ABIN2792592
发货至: 中国
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Quick Overview for ETV6 抗体 (C-Term) (ABIN2792592)

抗原

See all ETV6 抗体
ETV6 (Ets Variant 6 (ETV6))

适用

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人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, 马, 兔, 豚鼠

宿主

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克隆类型

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多克隆

标记

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This ETV6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    序列

    VSVSPPEEHA MPIGRIADCR LLWDYVYQLL SDSRYENFIR WEDKESKIFR

    交叉反应

    牛, 犬, 小鸡, 人, 小鼠, 大鼠

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

    产品特性

    This is a rabbit polyclonal antibody against ETV6. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human ETV6
  • 应用备注

    WB Suggested Anti-ETV6 Antibody Titration: 0.2-1 µg/mL
    ELISA Titer: 1:1562500
    Positive Control: Jurkat cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 452 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    ETV6 (Ets Variant 6 (ETV6))

    别名

    ETV6 / TEL1

    背景

    ETV6 (ETS-related protein Tel1, ETS translocation variant 6 , Tel) is an ETS family transcription factor. This protein contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: TEL, TEL/ABL
    Protein Interaction Partner: AP1M1, WDYHV1, UBC, SUMO1, NEDD8, ETV6, SUMO2, PIN1, HDAC6, SOX2, TRAF3, SOCS3, SOCS1, PDGFRB, ELAVL1, UBE2I, NCOR1, SIN3A, HDAC3, L3MBTL1, SMURF1, HDAC9, KAT5, FLI1, IRF8, SKP1, FBXL6, GAB2, GRB2, CRKL, ACTA1,
    Protein Size: 452

    分子量

    53 kDa

    基因ID

    2120

    NCBI登录号

    NM_001987, NP_001978

    UniProt

    P41212
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