SOX8 抗体 (C-Term)
Quick Overview for SOX8 抗体 (C-Term) (ABIN2792566)
抗原
See all SOX8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- ASPTETGPPR PHIKTEQPSP GHYGDQPRGS PDYGSCSGQS SATPAAPAGP
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交叉反应
- 犬, 人, 小鼠, 大鼠
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预测反应
- Cow: 92%, Dog: 92%, Guinea Pig: 85%, Horse: 92%, Human: 100%, Mouse: 78%, Rat: 85%
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产品特性
- This is a rabbit polyclonal antibody against SOX8. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human SOX8
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应用备注
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WB Suggested Anti-SOX8 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:12500
Positive Control: Hela cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. -
说明
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Antigen size: 446 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SOX8 (SRY (Sex Determining Region Y)-Box 8 (SOX8))
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别名
- SOX8
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背景
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SOX8 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).
Alias Symbols: MGC24837
Protein Interaction Partner: JAM2, PIDD1, NOD1, UBC, MMP1, SOX2, HOXC11, UTF1, PAX3, OLIG2, HHEX, POU3F3, TCF12, DLX5, SP1, NR5A1, JUN, POU5F1, EGR2, CEBPA,
Protein Size: 446 -
分子量
- 47 kDa
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基因ID
- 30812
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NCBI登录号
- NM_014587, NP_055402
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UniProt
- P57073
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途径
- Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
抗原
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