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SOX8 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects SOX8 in WB. It exhibits reactivity toward 人, 小鼠, 大鼠, 豚鼠, Cow, 犬 和 马.
产品编号 ABIN2792566
发货至: 中国
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Quick Overview for SOX8 抗体 (C-Term) (ABIN2792566)

抗原

See all SOX8 抗体
SOX8 (SRY (Sex Determining Region Y)-Box 8 (SOX8))

适用

人, 小鼠, 大鼠, 豚鼠, Cow, 犬, 马

宿主

  • 38
  • 4
  • 1

克隆类型

  • 40
  • 3
多克隆

标记

  • 14
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SOX8 antibody is un-conjugated

应用范围

  • 32
  • 19
  • 13
  • 13
  • 4
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    ASPTETGPPR PHIKTEQPSP GHYGDQPRGS PDYGSCSGQS SATPAAPAGP

    交叉反应

    犬, 人, 小鼠, 大鼠

    预测反应

    Cow: 92%, Dog: 92%, Guinea Pig: 85%, Horse: 92%, Human: 100%, Mouse: 78%, Rat: 85%

    产品特性

    This is a rabbit polyclonal antibody against SOX8. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human SOX8
  • 应用备注

    WB Suggested Anti-SOX8 Antibody Titration: 0.2-1 µg/mL
    ELISA Titer: 1:12500
    Positive Control: Hela cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 446 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    SOX8 (SRY (Sex Determining Region Y)-Box 8 (SOX8))

    别名

    SOX8

    背景

    SOX8 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).
    Alias Symbols: MGC24837
    Protein Interaction Partner: JAM2, PIDD1, NOD1, UBC, MMP1, SOX2, HOXC11, UTF1, PAX3, OLIG2, HHEX, POU3F3, TCF12, DLX5, SP1, NR5A1, JUN, POU5F1, EGR2, CEBPA,
    Protein Size: 446

    分子量

    47 kDa

    基因ID

    30812

    NCBI登录号

    NM_014587, NP_055402

    UniProt

    P57073

    途径

    Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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