NFX1 抗体 (Middle Region)
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北京 101111
Quick Overview for NFX1 抗体 (Middle Region) (ABIN2792551)
抗原
See all NFX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- TLTGVLEREM QARPPPPIPH HRHQSDKNPG SSNLQKITKE PIIDYFDVQD
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交叉反应
- 牛, 犬, 人, 小鼠, 大鼠
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预测反应
- Cow: 85%, Dog: 85%, Human: 100%, Mouse: 76%, Rabbit: 85%, Rat: 85%
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产品特性
- This is a rabbit polyclonal antibody against NFX1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human NFX1
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anti-Nuclear Transcription Factor, X-Box Binding 1 (NFX1) (AA 981-1080) antibody
NFX1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1D12 unconjugated
anti-Nuclear Transcription Factor, X-Box Binding 1 (NFX1) (C-Term) antibodyNFX1 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 猴 WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Transcription Factor, X-Box Binding 1 (NFX1) (N-Term) antibodyNFX1 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB Suggested Anti-NFX1 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. -
说明
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Antigen size: 1120 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NFX1 (Nuclear Transcription Factor, X-Box Binding 1 (NFX1))
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别名
- NFX1
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背景
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MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. NFX1 is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma.MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified.
Alias Symbols: DKFZp779G2416, MGC20369, NFX2
Protein Interaction Partner: UBC, BMI1, HECW2, SRSF4, SRSF3, RPS19, RPS3A, RPL22, RPL17, RPL13, RPL7A, RPL6, RPL3, PABPC3, YBX1, NCL, HNRNPM, HSPA1A, HNRNPU, HNRNPH1, HNRNPA2B1, HIST1H2AE, EEF1A2, DMD, DDX5, FAM208B, PABPC1, RPL13A, LARP1, APC2, MATR3, HIST1H4E, USP9X, SIN3A, MAML3,
Protein Size: 1120 -
分子量
- 124 kDa
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基因ID
- 4799
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NCBI登录号
- NM_002504, NP_002495
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UniProt
- Q12986
抗原
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