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DEK 抗体 (Middle Region)

This anti-DEK antibody is a 兔 多克隆 antibody detecting DEK in WB. Suitable for 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 马 和 Pig. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2792529
发货至: 中国

Quick Overview for DEK 抗体 (Middle Region) (ABIN2792529)

抗原

See all DEK 抗体
DEK (DEK Oncogene (DEK))

适用

  • 47
  • 22
  • 11
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  • 3
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  • 1
  • 1
人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 马, Pig

宿主

  • 60
  • 2

克隆类型

  • 47
  • 15
多克隆

标记

  • 28
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  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DEK antibody is un-conjugated

应用范围

  • 44
  • 23
  • 23
  • 19
  • 13
  • 13
  • 12
  • 10
  • 10
  • 9
  • 3
  • 2
  • 2
Western Blotting (WB)
  • 抗原表位

    • 15
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Middle Region

    序列

    ELKETIKKLL ASANLEEVTM KQICKKVYEN YPTYDLTERK DFIKTTVKEL

    交叉反应

    牛, 小鸡, 人, 小鼠, 大鼠

    预测反应

    Cow: 85%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 85%, Pig: 78%, Rabbit: 85%, Rat: 85%

    产品特性

    This is a rabbit polyclonal antibody against DEK. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human DEK
  • 应用备注

    WB Suggested Anti-DEK Antibody Titration: 0.2-1 µg/mL
    ELISA Titer: 1:1562500
    Positive Control: MCF7 cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 375 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Chen, Gao, Hu, Pang, Cai, Li, Wu, Jiang: "Galactose-poly(ethylene glycol)-polyethylenimine for improved lung gene transfer." in: Biochemical and biophysical research communications, Vol. 375, Issue 3, pp. 378-83, (2008) (PubMed).

  • 抗原

    DEK (DEK Oncogene (DEK))

    别名

    DEK

    背景

    DEK is a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene.This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene and the presence of antibodies against this protein are all associated with various diseases. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: D6S231E
    Protein Interaction Partner: CUL3, SPOP, UBC, EED, IRF2BP2, GANAB, PTPN12, CSNK2A2, CSNK2A1, TP53BP1, ESR1, VTN, S100A9, RPL37A, DHX15, FTSJ3, WIBG, TMED9, EXOSC2, UTP14A, THRAP3, CAND1, COPS5, CDK2, YWHAZ, Cebpb, ELAVL1, SUMO1, SUMO2, RAD21, HDGF, KAT2B, EP300, CREBBP, HIST1H4A, HDA
    Protein Size: 375

    分子量

    43 kDa

    基因ID

    7913

    NCBI登录号

    NM_003472, NP_003463

    UniProt

    P35659
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